Comparison of technical failures and patient-related adverse events associated with 3 widely used mechanical lithotripters for ERCP: insights from the U.S. Food and Drug Administration Manufacturer and User Facility Device Experience database

Post written by Douglas G. Adler, MD, FACG, AGAF, FASGE, from the Center for Advanced Therapeutic Endoscopy, Centura Health, Denver, Colorado, USA, and incoming GIE Editor-in-Chief. We analyzed the U.S. Food and Drug Administration’s Manufacturer and User Facility Device Experience (MAUDE) database for all reports of patient-related adverse events and device failures associated with the 3 …

Continue reading Comparison of technical failures and patient-related adverse events associated with 3 widely used mechanical lithotripters for ERCP: insights from the U.S. Food and Drug Administration Manufacturer and User Facility Device Experience database

Bacterial contamination and organic residue after reprocessing in duodenoscopes with disposable distal caps compared with duodenoscopes with fixed distal caps: a randomized trial

Post written by Wiriyaporn Ridtitid, MD, and Rungsun Rerknimitr, MD, from the Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, and the Excellence Center for Gastrointestinal Endoscopy, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. The focus of this randomized trial was to compare bacterial contamination evaluated by culture between duodenoscopes with disposable distal caps …

Continue reading Bacterial contamination and organic residue after reprocessing in duodenoscopes with disposable distal caps compared with duodenoscopes with fixed distal caps: a randomized trial

Protein biomarkers in pancreatic juice and serum for identification of pancreatic cancer

Post written by Iris J.M. Levink, MD, from the Department of Gastroenterology & Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands. We aimed to develop a panel of biomarkers from serum and pancreatic juice (PJ) to detect pancreatic ductal adenocarcinoma for future surveillance purposes. This study focused on the performance of proteins (interleukin-8 [IL-8]; interferon-γ [IFN-γ]; …

Continue reading Protein biomarkers in pancreatic juice and serum for identification of pancreatic cancer

Safety and efficacy of over-the-scope clips versus standard therapy for high-risk nonvariceal upper GI bleeding: systematic review and meta-analysis

Post written by Jay Bapaye, MD, from the Department of Internal Medicine, Rochester General Hospital, Rochester, New York, USA. This study compared the safety and efficacy of over-the-scope clips (OTSCs) and standard therapy for high-risk nonvariceal upper GI bleeding (NVUGIB). Upper GI bleeding carries a high risk of morbidity and mortality. Endoscopic therapy aims at achieving …

Continue reading Safety and efficacy of over-the-scope clips versus standard therapy for high-risk nonvariceal upper GI bleeding: systematic review and meta-analysis

Tip-in EMR as an alternative to endoscopic submucosal dissection for 20- to 30-mm nonpedunculated colorectal neoplasms

Post written by Kazunori Takada, MD, and Kinichi Hotta, MD, from the Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan. Compared with conventional EMR, endoscopic submucosal dissection (ESD) provides a higher en-bloc resection rate and a lower local recurrence rate for large lesions. However, ESD is technically demanding and associated with a higher risk of adverse …

Continue reading Tip-in EMR as an alternative to endoscopic submucosal dissection for 20- to 30-mm nonpedunculated colorectal neoplasms

Comparison of focal cryoballoon ablation with 10- and 8-second doses for treatment of Barrett’s esophagus–related neoplasia: results from a prospective European multicenter study (with video)

Post written by Charlotte N. Frederiks, MD, from the Department of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, the Netherlands, and the Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. Focal cryoballoon ablation is investigated for the treatment of Barrett’s esophagus–related neoplasia in a European multicenter study known as the …

Continue reading Comparison of focal cryoballoon ablation with 10- and 8-second doses for treatment of Barrett’s esophagus–related neoplasia: results from a prospective European multicenter study (with video)

Clinical utility of purgative bowel preparation before capsule endoscopy: a multicenter, blinded, randomized controlled trial

Post written by Mehul Lamba, FRACP, from the Department of Gastroenterology and Hepatology, Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia. Capsule endoscopy (CE) is an investigation of choice for the assessment of suspected small intestinal bleeding. Because CE lacks the ability to wash or suction intestinal contents, diagnostic utility is reliant on adequate small-bowel preparation. …

Continue reading Clinical utility of purgative bowel preparation before capsule endoscopy: a multicenter, blinded, randomized controlled trial

Aerosol and droplet generation in upper and lower GI endoscopy: whole procedure and event-based analysis

Post written by Adolfo Parra-Blanco, MD, PhD, from the Department of Gastroenterology, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, and Nottingham Digestive Diseases Centre, and George S.D. Gordon, PhD, from the Optics and Photonics Group, Faculty of Engineering, University of Nottingham, Nottingham, UK. The aim of this prospective study …

Continue reading Aerosol and droplet generation in upper and lower GI endoscopy: whole procedure and event-based analysis

Submucosal tunneling endoscopic septum division for esophageal diverticulum with a median follow-up of 39 months: a multicenter cohort study

Post written by Ping-Hong Zhou, MD, FASGE, from the Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, and Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China. In this study, we primarily focused on the safety and efficacy of submucosal tunneling endoscopic septum division (STESD) for patients with esophageal diverticulum and STESD’s impact on patients’ …

Continue reading Submucosal tunneling endoscopic septum division for esophageal diverticulum with a median follow-up of 39 months: a multicenter cohort study

Improving diagnostic accuracy and appropriate indications for surgery in pancreatic cystic neoplasms: the role of EUS

Post written by Stefano Crippa, MD, PhD, from the Division of Pancreatic Surgery, IRCCS San Raffaele Scientific Institute, and Vita Salute San Raffaele University, Milan, Italy, Fabio Giannone, MD, from the Division of Pancreatic Surgery, IRCCS San Raffaele Scientific Institute, and the Department of General, Digestive and Endocrine Surgery, University Hospital of Strasbourg, Strasbourg, France, and …

Continue reading Improving diagnostic accuracy and appropriate indications for surgery in pancreatic cystic neoplasms: the role of EUS