Colorectal cancer in 18- to 49-year-olds: rising rates, presentation, and outcome in a large integrated health system

Post written by Nimish Vakil, MD, from the Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, and the Department of Gastroenterology, Advocate Aurora Health, Milwaukee, Wisconsin, USA. Colon cancer is rising in young people and the cause is unknown. There is little information on outcomes in this group. Colorectal cancer …

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Single-pass 1-needle actuation versus single-pass 3-needle actuation technique for EUS-guided liver biopsy sampling

Post written by David L. Diehl, MD, FACP, FASGE, from the Department of Gastroenterology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA. The focus of this study is to further refine the optimal method for EUS-guided liver biopsy. Some reports in the literature utilize a single pass, single-needle throw for obtaining a liver biopsy specimen. …

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Validation of a methylated DNA marker panel for the nonendoscopic detection of Barrett’s esophagus in a multisite case-control study

Post written by Prasad G. Iyer, MD, MSc, from the Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, Minnesota, USA. This article summarizes the third step in the development and validation of a nonendoscopic, minimally invasive molecular test to detect a precursor to esophageal adenocarcinoma: Barrett’s esophagus. Esophageal adenocarcinoma is a rare but lethal malignancy …

Continue reading Validation of a methylated DNA marker panel for the nonendoscopic detection of Barrett’s esophagus in a multisite case-control study

Editor’s Choice: Laparoscopic versus EUS-guided gastroenterostomy for gastric outlet obstruction

GIE Associate Editor, Dr. Fauze Maluf-Filho, highlights this article from the September issue “Laparoscopic versus EUS-guided gastroenterostomy for gastric outlet obstruction: an international multicenter propensity score–matched comparison” by Michiel Bronswijk, MD, et al. In this observational, multicenter study, the authors compared the outcomes of EUS-guided gastroenterostomy versus the gold standard intervention, laparoscopic gastroenterostomy, for the treatment …

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Novel approaches to minimize intraoperative bleeding during ESD of a large rectal lateral spreading tumor extended to the dentate line with internal hemorrhoids

Post written by Fabian Emura, MD, PhD, FASGE, from the Division of Gastroenterology, Universidad de La Sabana, Chía, and the Advanced GI Endoscopy, EmuraCenter LatinoAmerica, Bogotá DC, Colombia. This video case describes how we applied surgically vascular control principles to reduce the risk of adverse events during third space endoscopy. As the risk of bleeding …

Continue reading Novel approaches to minimize intraoperative bleeding during ESD of a large rectal lateral spreading tumor extended to the dentate line with internal hemorrhoids

EUS-guided gallbladder drainage: Where will we go next?

Post written by Mihai Rimbaş, MD, PhD, and Alberto Larghi, MD, PhD, from the Gastroenterology Department, Colentina Clinical Hospital; the Department of Internal Medicine, Carol Davila University of Medicine, Bucharest, Romania; the Digestive Endoscopy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS; and the Center for Endoscopic Research Therapeutics and Training, Catholic University, Rome, Italy. We …

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Acute physiologic effects of N95 respirator use on gastroenterologists performing simulated colonoscopy

Post written by Asif Khalid, MD, from the VA Pittsburgh HealthCare System, and the University of Pittsburgh Medical System, Pittsburgh, Pennsylvania, USA. Gastroenterologists and GI lab staff are required to use N95 respirators while performing aerosol generating endoscopic procedures during the SARS-CoV-2 pandemic. Unfortunately, N95 respirator use is associated with the development of multiple symptoms. …

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Endoscopic radiofrequency ablation plus plastic stent placement versus stent placement alone for unresectable extrahepatic biliary cancer

Post written by Bing Hu, MD, PhD, from the Department of Gastroenterology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Yangpu District, and the Department of Gastroenterology, Third Affiliated Hospital, Second Military Medical University, Jiading District, Shanghai, China. The focus of our study is to compare the efficacy and safety between endoscopic radiofrequency ablation (RFA) …

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Combination of a dynamic rigidizing overtube and a novel injectable needle-type knife to facilitate colorectal endoscopic submucosal dissection

Post written by Martin Coronel, MD, and Phillip S. Ge, MD, from the Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas. A 66-year-old man was referred for endoscopic resection of a 35-mm laterally spreading tumor at the hepatic flexure (Paris IIa+Is). A previous EMR attempt was unsuccessful …

Continue reading Combination of a dynamic rigidizing overtube and a novel injectable needle-type knife to facilitate colorectal endoscopic submucosal dissection

Gastric peroral endoscopic myotomy for the treatment of refractory gastroparesis

Post written by Mohammad Al-Haddad, MD, from the Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA. The study focused on prospectively assessing the safety and efficacy of gastric peroral endoscopic myotomy in improving symptoms, quality of life, and healthcare resource utilization in a cohort of gastroparesis patient that had failed …

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