Efficacy and histologic accuracy of underwater versus conventional endoscopic mucosal resection for large (>20 mm) colorectal polyps

Post written by Saurabh Chandan, MD, from the Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, Nebraska, USA. Underwater endoscopic mucosal resection (U-EMR) is a simple and easy-to-learn technique for resection of colorectal lesions. It eliminates the need of using submucosal injection to “lift” the lesion prior to resection. The main aim of our …

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Evaluating the impact of frailty on periprocedural adverse events and mortality among patients with GI bleeding

Post written by Camilo J. Acosta, MD David Goldberg, MD Sunil Amin, MD, MPH, from the Department of Medicine, University of Miami/Jackson Memorial Hospital, Miami, Florida, USA and Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA. Frailty is common and has been extensively studied as a …

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Impact of margin status on outcomes after endoscopic resection of well-differentiated duodenal neuroendocrine tumors

Post written by Shruti Mony, MD, from the Department of Gastroenterology, Johns Hopkins University, Baltimore, Maryland, USA. The focus of our study was to assess the recurrence patterns after endoscopic resection of nonampullary duodenal neuroendocrine tumors [DNETs]. Specifically, we wanted to identify the risk factors, effect of positive histologic margins, and optimal surveillance strategies including …

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Colorectal cancer in 18- to 49-year-olds: rising rates, presentation, and outcome in a large integrated health system

Post written by Nimish Vakil, MD, from the Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, and the Department of Gastroenterology, Advocate Aurora Health, Milwaukee, Wisconsin, USA. Colon cancer is rising in young people and the cause is unknown. There is little information on outcomes in this group. Colorectal cancer …

Continue reading Colorectal cancer in 18- to 49-year-olds: rising rates, presentation, and outcome in a large integrated health system

Single-pass 1-needle actuation versus single-pass 3-needle actuation technique for EUS-guided liver biopsy sampling

Post written by David L. Diehl, MD, FACP, FASGE, from the Department of Gastroenterology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA. The focus of this study is to further refine the optimal method for EUS-guided liver biopsy. Some reports in the literature utilize a single pass, single-needle throw for obtaining a liver biopsy specimen. …

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Validation of a methylated DNA marker panel for the nonendoscopic detection of Barrett’s esophagus in a multisite case-control study

Post written by Prasad G. Iyer, MD, MSc, from the Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, Minnesota, USA. This article summarizes the third step in the development and validation of a nonendoscopic, minimally invasive molecular test to detect a precursor to esophageal adenocarcinoma: Barrett’s esophagus. Esophageal adenocarcinoma is a rare but lethal malignancy …

Continue reading Validation of a methylated DNA marker panel for the nonendoscopic detection of Barrett’s esophagus in a multisite case-control study

Soft palate findings associated with a high risk of esophageal squamous cell carcinoma using an endoscopic system with enhanced depth-of-field imaging

Post written by Kotaro Waki, MD, from the Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan. We previously reported that 3 endoscopic findings of melanosis, whitish epithelium, and vasodilation in the soft palate are associated with a high risk of esophageal squamous cell carcinoma (ESCC) and are considered useful as indicators of ESCC. …

Continue reading Soft palate findings associated with a high risk of esophageal squamous cell carcinoma using an endoscopic system with enhanced depth-of-field imaging

EUS-guided gallbladder drainage: Where will we go next?

Post written by Mihai Rimbaş, MD, PhD, and Alberto Larghi, MD, PhD, from the Gastroenterology Department, Colentina Clinical Hospital; the Department of Internal Medicine, Carol Davila University of Medicine, Bucharest, Romania; the Digestive Endoscopy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS; and the Center for Endoscopic Research Therapeutics and Training, Catholic University, Rome, Italy. We …

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GI endoscopic submucosal dissection using a calibrated, small-caliber-tip, transparent hood for lesions with fibrosis

Post written by Tatsuma Nomura, MD, from the Department of Gastroenterology, Mie Prefectural Shima Hospital, Shima, and the Department of Gastroenterology, Ise Red Cross Hospital, Ise, Mie, Japan. We describe a novel technique for overcoming severe fibrosis encountered during endoscopic submucosal dissection (ESD) using a calibrated, small-caliber tip, transparent hood (CAST hood) with Pocket-creation method …

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Acute physiologic effects of N95 respirator use on gastroenterologists performing simulated colonoscopy

Post written by Asif Khalid, MD, from the VA Pittsburgh HealthCare System, and the University of Pittsburgh Medical System, Pittsburgh, Pennsylvania, USA. Gastroenterologists and GI lab staff are required to use N95 respirators while performing aerosol generating endoscopic procedures during the SARS-CoV-2 pandemic. Unfortunately, N95 respirator use is associated with the development of multiple symptoms. …

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