Category: Investigations

Immunohistologic analysis of the duodenal bulb

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Post written by Tarcisio Not, MD, from the Institute for Maternal and Child Health–IRCCS “Burlo Garofolo” Trieste, Trieste, Italy. This prospective study investigates whether histological analysis of the duodenal bulb combined with intestinal IgA anti-tissue transglutamonase deposit immunoassay makes celiac disease diagnosis possible in at-risk children with low concentrations of serum anti-tissue transglutaminase. Anti-tissue transglutaminase …

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Editor’s Choice: Screening for esophageal squamous cell carcinoma

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Associate Editor, Dr. Fauze Maluf-Filho, highlights this article from the September issue “Screening for esophageal squamous cell carcinoma: recent advances” by Don C. Codipilly, MD, et al.  This study provides a thorough review of the current technologies (endoscopic and non-endoscopic) to screen for esophageal squamous cell carcinoma (ESCC). It also points out future directions for …

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Transplantation of autologous esophageal mucosa

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Post written by JianYing Bai, PhD, from the Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, China. We focused on the effectiveness and safety of endoscopic transplantation of autologous esophageal mucosa in preventing stricture formation after circumferential ESD. Esophageal stricture is a very common adverse event after ESD, especially with resection of nearly …

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Recurrent acute pancreatitis in a toddler: a “wormy surprise”

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Post written by Zaheer Nabi, MD, DNB, from the Asian Institute of Gastroenterology, Hyderabad, India. The video case describes a 3-year-old child presenting with recurrent episodes of acute pancreatitis. Etiological evaluation revealed multiple calculi in the gallbladder on transabdominal ultrasonography. Expecting a calculus in the bile duct, we performed an endosonography to confirm. Surprisingly, endosonography …

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Comparing EUS-GG-ERCP and e-ERCP in patients with RYGB

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Post written by Majidah Bukhari, MBBS, MD, FRCPC, from the Department of Medicine and Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA, and King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia. Roux-en-Y gastric bypass (RYGB) remains one of the most commonly performed bariatric surgeries worldwide. ERCP in patients with …

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Successful removal of duodenal submucosal tumors with ESD

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Post written by Hiroyuki Aihara, MD, PhD, FASGE, from the Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA. Endoscopic submucosal dissection (ESD) allows for en bloc resection of gastrointestinal lesions, which theoretically results in lower recurrence rates. However, ESD in the duodenal bulb is technically challenging …

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Multifocal nitrous oxide cryoballoon ablation

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Post written by Marcia Irene Canto, MD, MHS, from the Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA. This article discusses a novel method for endoscopic eradication of neoplastic Barrett’s esophagus. We need to develop additional safe and effective approaches to treat Barrett’s esophagus and expand our endoscopic toolkit. In a …

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