“Underwater” ESD for superficial esophageal neoplasms

Post written by Tomofumi Akasaka from the Department of Gastrointestinal Oncology at Osaka Medical Center for Cancer and Cardiovascular Disease. In this study, we used a bipolar needle-knife with a water jet function (Jet B-knife; Zeon Medical, Tokyo, Japan). After a circumferential incision, as performed for conventional ESD, esophageal lumen was filled and submucosal injection with …

Continue reading “Underwater” ESD for superficial esophageal neoplasms

Comparison of prognosis between gastric ESD and surgery

Post written by Shusei Fukunaga, MD, PhD and  Yasuaki Nagami, MD, PhD from the Department of Gastroenterology at Osaka City University Graduate School of Medicine in Osaka. Our study focused on the long-term outcomes, risk factors for mortality, and adverse events for patients with expanded-indication lesions of differentiated-type early gastric cancer (EGC) who underwent endoscopic …

Continue reading Comparison of prognosis between gastric ESD and surgery

Clinical Utility of Rapid On-site Cytopathology

Post written by Dr. Harry Aslanian from the Section of Digestive Diseases at Yale University. We thought it would be interesting for non-endosonographers to see how easily and quickly ROSE can provide diagnostic information. Among endosonographers, there is local variation in cytopathologists’ comfort level with pancreas cytology and variable interest in ROSE. While some centers have …

Continue reading Clinical Utility of Rapid On-site Cytopathology

Impact of carbon dioxide insufflation and water exchange on postcolonoscopy outcomes

Post written by Sergio Cadoni from the Digestive Endoscopy Unit at St. Barbara Hospital in Iglesias, Italy. Water exchange (WE) is the least painful insertion method during colonoscopy. However, its impact on postcolonoscopy discomfort has not been well-described. Carbon dioxide (CO2) insufflation has been consistently shown to decrease postcolonoscopy discomfort. We compared postcolonoscopy outcomes of various combinations …

Continue reading Impact of carbon dioxide insufflation and water exchange on postcolonoscopy outcomes

EUS-guided coiling for bleeding duodenal collateral vessel

Dr. Roy J Mukkada, MD, DNB, from the Department of Gastroenterology & Hepatology, VPS Lakeshore Hospital, Kochi, Kerala, India, presents this video case. A 65-year-old man (an alcoholic and a smoker) presented with recurrent abdominal pain, weight loss, and loss of appetite. He was known to have had chronic calcific pancreatitis since 2014. CT of …

Continue reading EUS-guided coiling for bleeding duodenal collateral vessel

EUS-guided fine needle biopsy sampling using a novel fork-tip needle

Post written by Pujan Kandel, MD, from the Division of Gastroenterology, Mayo Clinic, Jacksonville, Florida. This was a single center retrospective case control study. All the consecutive samples from EUS-FNB-SCs were matched in a 1:3 ratio by the lesion site (e.g. pancreatic head) and needle gauge (i.e. 19, 22, and 25 gauge) to recent random …

Continue reading EUS-guided fine needle biopsy sampling using a novel fork-tip needle

Successful management of ischemic cholangiopathy

Saikiran Raghavapuram, MD, Mohit Girotra, MD, FACP, and Benjamin Tharian, MD, MRCP, FRACP, from the University of Arkansas for the Medical Sciences present this video case. We present a 63-year-old male with a history of orthotopic liver transplantation 3 years ago, who presented with cholestatic jaundice. Work up revealed severe stricture of proximal common bile …

Continue reading Successful management of ischemic cholangiopathy

The use of hemostatic spray as an adjunct to conventional hemostatic measures

Post written by Rohit Sinha, MBBS, MRCP, PgDip, from the Royal Infirmary and The University of Edinburgh, Edinburgh, United Kingdom. We wanted to evaluate the efficacy of Hemospray in conjunction with established hemostatic endo-therapy in a high-risk nonvariceal upper GI bleeding setting. There was no evidence about the efficacy and outcome of combination therapy (Hemospray …

Continue reading The use of hemostatic spray as an adjunct to conventional hemostatic measures

Mating Ancylostoma Duodenale under Magnifying Endoscopy

Ming-Yan Cai, MD, from the Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China, presents this video case. During a regular EGD exam, using a magnifying scope with narrow-band imaging (NBI) function, we observed a very interesting pattern of Ancylostoma duodenale. A male worm was coiled around a female one and the …

Continue reading Mating Ancylostoma Duodenale under Magnifying Endoscopy

Molecular cytology genotyping of primary and metastatic GI stromal tumors

Post written by Ferga C. Gleeson, MD, from the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. In patients with either primary or metastatic sporadic GI stromal tumors, we sought to determine the frequency of KIT and PDGFRA pathogenic alterations within paired endoscopic ultrasound cytology smears and surgical pathology specimens, Imatinib sensitivity, and the …

Continue reading Molecular cytology genotyping of primary and metastatic GI stromal tumors