Post written by Jessica R. Allegretti, MD, MPH, from Brigham Women’s Hospital, Boston, Massachusetts, USA. Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Recently, fecal microbiota transplantation (FMT) has emerged as an effective and safe therapy for recurrent CDI; however, there is no standardized clinical approach. Given the rapid …
Category: GIE
Prior gastroscopy and mortality in patients with gastric cancer
Post written by Wai K. Leung, MD, from the Department of Medicine, University of Hong Kong, Hong Kong, China. Gastric cancer is still the fifth most common cancer in the world with approximately one million new patients being diagnosed each year. Although upper endoscopy remains the gold standard for diagnosis of gastric cancer and pre-neoplastic …
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Acellular dermal matrix for esophageal stricture prevention after ESD in a porcine model
Post written by Siyu Sun MD, PhD, and Ye Han MD, PhD, from the Endoscopic Center, Shengjing Hospital of China Medical University, Shenyang, China. Esophageal stenosis is closely associated with quasi-circumferential endoscopic submucosal dissection (ESD). We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane in a large …
Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia
Post written by Eiichiro Yamamoto, MD, PhD, Yoshihito Tanaka, MD, and Hiromu Suzuki, MD, PhD, from the Department of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo, Japan, and the Department of Digestive Disease Center, Akita Red Cross Hospital, Akita, Japan. Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with …
Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding
Post written by Navin L. Kumar, MD and John R. Saltzman, MD, from the Brigham and Women’s Hospital, Division of Gastroenterology, Hepatology and Endoscopy, and Harvard Medical School, Boston, Massachusetts. The focus of our study was to assess whether an increase in blood urea nitrogen (BUN) at 24 hours of presentation is predictive of worse …
Editor’s Choice: Impact of mucosal inflammation on risk of colorectal neoplasia
GIE Editor-in-Chief, Dr. Michael Wallace, highlights this article from the December issue, “Impact of mucosal inflammation on risk of colorectal neoplasia in patients with ulcerative colitis: a systematic review and meta-analysis” by Brisas M. Flores, MD, et al. Endoscopy is playing an increasing role in the management of patients with IBD. The special December issue …
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Development and reliability of the new endoscopic virtual chromoendoscopy score
Post written by Marietta Iacucci, MD, PhD, from the NIHR Biomedical Research Centre, Institution of Translational Medicine, University of Birmingham, United Kingdom. Endoscopic scoring of mucosal inflammation and healing is widely used in clinical trials and increasingly in clinical practice. The current endoscopic scores are not precise in assessing minimal inflammatory changes or complete mucosal …
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Balloon enteroscopy vs spiral enteroscopy for small-bowel disorders
Post written by Ramkaji Baniya, MD, and Prabin Sharma, MD, from the Department of Internal Medicine, Hurley Medical Center, Michigan State University, Flint, Michigan, and the Department of Internal Medicine, Yale New Haven Health Bridgeport Hospital, Bridgeport, Connecticut. Our systematic review and meta-analysis aimed to compare the efficacy and safety of different deep enteroscopic procedures. …
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Bilateral vs unilateral placement of metal stents for inoperable high-grade malignant hilar biliary strictures
Post written by Tae Hoon Lee, MD, PhD, and Jong Ho Moon, MD, PhD, from the Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, and the Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Republic of Korea. There is no definite consensus on whether bilateral placement of metal …
Progressive learning in endoscopy simulation training improves clinical performance
Post written by Samir C. Grover, MD, MEd, FRCPC, from the Division of Gastroenterology, St. Michael’s Hospital Department of Medicine, University of Toronto, Toronto, Ontario, Canada. We aimed to improve existing simulation-based training curricula for teaching novices how to perform colonoscopy using progressive learning. We recognized that a theory-based approach to designing a curriculum in …
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