Editor’s Choice: Prior gastroscopy and mortality in patients with gastric cancer

Associate Editor, Dr. Lyndon Hernandez, MD, MPH, highlights this article from the January issue “Prior gastroscopy and mortality in patients with gastric cancer: a matched retrospective cohort study” by Wai K. Leung, MD, et al.  This nationwide observational study (n=20,066) showed a reduction in cancer-related mortality among patients who underwent gastroscopy within 5 years before …

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Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism

Post written by Vivek Kumbhari, MD, from the Department of Medicine and Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA. Gastric mucosal devitalization (GMD) rats had a lower body weight and reduced intrabdominal adiposity compared with sham surgery rats. The morphologic findings at 8 weeks postoperative were compared with those …

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Cap cuff–assisted colonoscopy vs standard colonoscopy for adenoma detection

Post written by Giovanni D. De Palma, MD, from Department of Clinical Medicine and Surgery, University Federico II of Naples, School of Medicine, Naples, Italy. Our paper presents a single-center, randomized, back-to-back trial which was designed to investigate the contribution of the EndoCuff device to the improvement of the adenoma eetection rate in the course …

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The SAFE-T assessment tool

Post written by Navin L. Kumar, MD and John R. Saltzman, MD, from Brigham and Women’s Hospital, Division of Gastroenterology, Hepatology and Endoscopy, and Harvard Medical School, Boston, Massachusetts, USA. The focus of our study was to develop and validate a concise assessment tool to evaluate real-time fellow performance in colonoscopy via a web-based application …

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The EPISOD study: long-term outcomes

Post written by Peter B. Cotton, MD, FRCS, FRCP, from the Medical University of South Carolina, Charleston, South Carolina, USA. The EPISOD study randomized 214 patients with post-cholecystectomy pain and little or no evidence of biliary obstruction (SOD type III) to sphincterotomy or sham intervention at ERCP. Intervention was judged successful at 1 year (by …

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The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection

Post written by Jessica R. Allegretti, MD, MPH, from Brigham Women’s Hospital, Boston, Massachusetts, USA. Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Recently, fecal microbiota transplantation (FMT) has emerged as an effective and safe therapy for recurrent CDI; however, there is no standardized clinical approach. Given the rapid …

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Prior gastroscopy and mortality in patients with gastric cancer

Post written by Wai K. Leung, MD, from the Department of Medicine, University of Hong Kong, Hong Kong, China. Gastric cancer is still the fifth most common cancer in the world with approximately one million new patients being diagnosed each year. Although upper endoscopy remains the gold standard for diagnosis of gastric cancer and pre-neoplastic …

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Acellular dermal matrix for esophageal stricture prevention after ESD in a porcine model

Post written by Siyu Sun MD, PhD, and Ye Han MD, PhD, from the Endoscopic Center, Shengjing Hospital of China Medical University, Shenyang, China. Esophageal stenosis is closely associated with quasi-circumferential endoscopic submucosal dissection (ESD). We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane in a large …

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Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia

Post written by Eiichiro Yamamoto, MD, PhD, Yoshihito Tanaka, MD, and Hiromu Suzuki, MD, PhD, from the Department of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo, Japan, and the Department of Digestive Disease Center, Akita Red Cross Hospital, Akita, Japan. Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with …

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Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding

Post written by Navin L. Kumar, MD and John R. Saltzman, MD, from the Brigham and Women’s Hospital, Division of Gastroenterology, Hepatology and Endoscopy, and Harvard Medical School, Boston, Massachusetts. The focus of our study was to assess whether an increase in blood urea nitrogen (BUN) at 24 hours of presentation is predictive of worse …

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