Post written by Prasad G. Iyer, MD, MSc, from the Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, Minnesota, USA. This article summarizes the third step in the development and validation of a nonendoscopic, minimally invasive molecular test to detect a precursor to esophageal adenocarcinoma: Barrett’s esophagus. Esophageal adenocarcinoma is a rare but lethal malignancy …
Tag: Barrett’s esophagus
Prevalence of Barrett’s esophagus and performance of societal screening guidelines in an unreferred primary care population of U.S. veterans
Post written by Theresa H. Nguyen, MD, from the Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, and the Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA. The focus of our study was to examine the prevalence of Barrett’s esophagus …
Barrett’s esophagus after sleeve gastrectomy: a systematic review and meta-analysis
Post written by Bashar J. Qumseya, MD, MPH, from the Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, Florida, USA. The study focused on the rate of Barrett’s esophagus (BE) in patients who undergo endoscopic sleeve gastrectomy (SG) for weight loss. My dentist informed me that he was seeing cases of very severe GERD …
Continue reading Barrett’s esophagus after sleeve gastrectomy: a systematic review and meta-analysis
Salvage circumferential ESD for refractory dysplastic Barrett’s esophagus
Post written by Robert Bechara, MD, from the Queens University, Kingston Health Sciences Center, Kingston, Ontario, Canada. A 64-year-old woman with a complex Barrett’s history was referred to our esophageal center. Her treatment history included endoscopic mucosal resection (EMR) with M3 intramucosal carcinoma and incomplete response to radiofrequency ablation (RFA) of the remaining Barrett’s, as …
Continue reading Salvage circumferential ESD for refractory dysplastic Barrett’s esophagus
AI using convolutional neural networks for real-time detection of early esophageal neoplasia in Barrett’s esophagus
Post written by Jason B. Samarasena, MD, from the H. H. Chao Comprehensive Digestive Disease Center, Division of Gastroenterology & Hepatology, Department of Medicine, University of California, Irvine, Orange, California, USA. Esophageal adenocarcinoma is actually rising in this country and not going down! The visual detection of early esophageal neoplasia in BE with white-light and …
Editor’s Choice: Deep learning algorithm detection of Barrett’s neoplasia with high accuracy during live endoscopic procedures
GIE Senior Associate Editor, Dr. Douglas G. Adler MD, FACG, AGAF, FASGE, highlights this article from the June issue “Deep learning algorithm detection of Barrett’s neoplasia with high accuracy during live endoscopic procedures” by Albert J. de Groof, MD, et al. Computer aided detection (CAD) is undergoing rapid development. It seems likely that, in the …
Risk of progression in Barrett’s esophagus indefinite for dysplasia
Post written by Rajesh Krishnamoorthi, MD, from the Digestive Diseases Institute, Virginia Mason Medical Center, Seattle, Washington, USA. The current study is systematic review and meta-analysis to estimate the risk of progression to high-grade dysplasia and/or esophageal adenocarcinoma in patients with Barrett's esophagus indefinite for dysplasia. Barrett’s esophagus (BE) is a precursor lesion for esophageal …
Continue reading Risk of progression in Barrett’s esophagus indefinite for dysplasia
Optimizing histopathologic evaluation of EMR specimens of Barrett’s esophagus–related neoplasia
Post written by Anouk Overwater, MD, from the Department of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, and the Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. The main question of this study is which specimen handling method results in an optimal histopathological evaluation of endoscopic resection specimens of …
Narrow-band imaging, volumetric laser endomicroscopy, and pathologic findings in Barrett’s esophagus
Post written by Norio Fukami, MD, AGAF, FACG, FASGE, from the Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona, USA. The case described in the video is a 36-year-old man with 10-year history of Barrett’s esophagus undergoing surveillance every 3 years who was referred for endoscopic resection on nodular dysplasia with cancer in the …
Outcome of EMR in Barrett’s esophagus determined by systematic quantification of epithelial glands using VLE
Post written by Amrit K. Kamboj, MD, and Cadman L. Leggett, MD, from the Department of Internal Medicine and Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA. Volumetric laser endomicroscopy (VLE) is an advanced imaging modality that uses optical coherence tomography to capture real-time, high-resolution, cross-sectional images of the esophagus. Epithelial glands are …
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