Post written by Peter B. Cotton, MD, FRCS, FRCP, from the Medical University of South Carolina, Charleston, South Carolina, USA. The EPISOD study randomized 214 patients with post-cholecystectomy pain and little or no evidence of biliary obstruction (SOD type III) to sphincterotomy or sham intervention at ERCP. Intervention was judged successful at 1 year (by …
Author: GIEjournal
The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection
Post written by Jessica R. Allegretti, MD, MPH, from Brigham Women’s Hospital, Boston, Massachusetts, USA. Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Recently, fecal microbiota transplantation (FMT) has emerged as an effective and safe therapy for recurrent CDI; however, there is no standardized clinical approach. Given the rapid …
Massive bleeding after EUS-guided walled-off necrosis drainage
Post written by Lady Katherine Mejia Perez, MD, and Victoria Gómez, MD, from the Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA. We describe a case of a 58-year-old man with necrotizing pancreatitis of biliary origin who underwent endoscopic drainage of a large, 12-cm pancreatic collection consistent with walled-off necrosis. A 15-mm diameter …
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Prior gastroscopy and mortality in patients with gastric cancer
Post written by Wai K. Leung, MD, from the Department of Medicine, University of Hong Kong, Hong Kong, China. Gastric cancer is still the fifth most common cancer in the world with approximately one million new patients being diagnosed each year. Although upper endoscopy remains the gold standard for diagnosis of gastric cancer and pre-neoplastic …
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EMR of large periampullary neuroendocrine tumor
Post written by Ahmed Akhter, MD, Eric M. Nelsen, MD, and Deepak V. Gopal, MD, FRCP(C), FASGE, from the Division of Gastroenterology and Hepatology, University of Wisconsin, Madison, Wisconsin. In our video, an elderly male with several comorbidities including chronic kidney disease and type-2 diabetes mellitus presented with a 2 day history of melena. He …
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Acellular dermal matrix for esophageal stricture prevention after ESD in a porcine model
Post written by Siyu Sun MD, PhD, and Ye Han MD, PhD, from the Endoscopic Center, Shengjing Hospital of China Medical University, Shenyang, China. Esophageal stenosis is closely associated with quasi-circumferential endoscopic submucosal dissection (ESD). We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane in a large …
EUS-guided rendezvous technique for refractory benign biliary stricture
Post written by Yukitoshi Matsunami, MD, from the Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan. In this video, we describe an EUS-guided rendezvous technique for refractory benign biliary stricture caused by postoperative bile-duct injury. A 60-year-old man underwent right-sided liver lobectomy for multiple liver metastases from an ascending colon cancer. After surgery, …
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Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia
Post written by Eiichiro Yamamoto, MD, PhD, Yoshihito Tanaka, MD, and Hiromu Suzuki, MD, PhD, from the Department of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo, Japan, and the Department of Digestive Disease Center, Akita Red Cross Hospital, Akita, Japan. Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with …
“Two-devices-in-one-channel method” in a Roux-en-Y patient
Post written by Yohei Koyama, MD, from the Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan. Balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (BE-ERCP) has improved the outcomes of ERCP in patients with surgically altered anatomy. However, BE-ERCP requires high technical expertise, and biliary cannulation is often difficult. An 83-year-old man previously underwent total gastrectomy …
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Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding
Post written by Navin L. Kumar, MD and John R. Saltzman, MD, from the Brigham and Women’s Hospital, Division of Gastroenterology, Hepatology and Endoscopy, and Harvard Medical School, Boston, Massachusetts. The focus of our study was to assess whether an increase in blood urea nitrogen (BUN) at 24 hours of presentation is predictive of worse …