Curative ESD of neoplasms in ulcerative colitis

Federico Iacopini, MD, from the Gastroenterology and Endoscopy Unit, Ospedale S. Giuseppe—ASL Roma H, Albano L, in Rome, Italy discusses this New Methods article “Curative endoscopic submucosal dissection of large nonpolypoid superficial neoplasms in ulcerative colitis (with videos).”

This is the first study evaluating the feasibility and clinical impact of endoscopic submucosal dissection (ESD) for non-polypoid superficial neoplasm in longstanding ulcerative colitis, traditionally considered a specific indication to surgery.

For the first time, this study suggests that non-polypoid superficial neoplasms in IBD can undergo endoscopic resection in an en bloc fashion regardless of their size and the highly prevalent submucosal fibrosis. Although significantly more difficult than in sporadic neoplasms, ESD achieves a high curative resection rate providing an accurate pathologic diagnosis. This study supports the evidence that endoscopic resection of IBD dysplastic lesions is an appropriate and effective alternative to surgery but requires a high level of expertise both for the delimitation and characterization of the lesion, and resection technique.

Find the abstract for this article online.

The information presented in Endoscopedia reflects the opinions of the authors and does not represent the position of the American Society for Gastrointestinal Endoscopy (ASGE). ASGE expressly disclaims any warranties or guarantees, expressed or implied, and is not liable for damages of any kind in connection with the material, information, or procedures set forth.

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