Pine-cone and villi patterns are signs suggestive of ulcerative colitis-associated colorectal cancer and dysplasia

Post written by Takahide Shinagawa, MD, from the Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan. How to survey colorectal cancer is one of the main problems in managing patients with ulcerative colitis (UC). Currently, colonoscopic surveillance is the gold standard and targeted biopsy for the suspicious lesions has become the focus of …

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Editor’s Choice: The emerging role of histologic disease activity assessment in ulcerative colitis

GIE Editor-in-Chief, Dr. Michael Wallace, highlights this article from the December issue “The emerging role of histologic disease activity assessment in ulcerative colitis” by Rish K. Pai, MD, PhD, et al.  The decision about when to start and stop therapy for ulcerative colitis is increasingly made based on colonoscopy and histological assessment of activity ("treat …

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The role of colorectal ESD in patients with ulcerative colitis

Post written by Satoshi Kinoshita, MD, Toshio Uraoka, MD, PhD, and Toshihiro Nishizawa, MD, PhD, from the Department of Gastroenterology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan, and the Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Maebashi, Japan. Patients with ulcerative colitis have an increased risk of colorectal dysplasia. Endoscopic …

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Development and reliability of the new endoscopic virtual chromoendoscopy score

Post written by Marietta Iacucci, MD, PhD, from the NIHR Biomedical Research Centre, Institution of  Translational  Medicine, University of Birmingham, United Kingdom. Endoscopic scoring of mucosal inflammation and healing is widely used in clinical trials and increasingly in clinical practice. The current endoscopic scores are not precise in assessing minimal inflammatory changes or complete mucosal …

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Confocal laser endomicroscopy in ulcerative colitis

John Gásdal Karstensen, MD, from the Gastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, in Copenhagen, Denmark, describes his article "Confocal laser endomicroscopy in ulcerative colitis: a longitudinal study of endomicroscopic changes and response to medical therapy (with videos)." The focus of this study was to correlate endomicroscopic mucosal features with disease activity and …

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Curative ESD of neoplasms in ulcerative colitis

Federico Iacopini, MD, from the Gastroenterology and Endoscopy Unit, Ospedale S. Giuseppe—ASL Roma H, Albano L, in Rome, Italy discusses this New Methods article "Curative endoscopic submucosal dissection of large nonpolypoid superficial neoplasms in ulcerative colitis (with videos)." This is the first study evaluating the feasibility and clinical impact of endoscopic submucosal dissection (ESD) for …

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