Christopher J. DiMaio, MD, FASGE, from the Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, in New York, New York, USA discusses his article "Pancreatic cyst fluid concentration of high-mobility group A2 protein acts as a differential biomarker of dysplasia in intraductal papillary mucinous neoplasm." No reliable cyst fluid biomarkers exist that …
Continue reading HMGA2 protein as a biomarker of dysplasia in IPMN
Rajesh Krishnamoorthi, MD, from the Division of Gastroenterology and Hepatology, Department of Internal Medicine, at Mayo Clinic in Rochester, Minnesota, USA discusses this systematic review and meta-analysis "Risk of recurrence of Barrett’s esophagus after successful endoscopic therapy." Endoscopic therapy is currently the treatment of choice for Barrett’s esophagus (BE) related dysplasia and mucosal adenocarcinoma. While …
Continue reading Risk of recurrence of BE after successful endoscopic therapy
Ken Hatogai, MD, from the Department of Gastroenterology, Endoscopy Division, at the National Cancer Center Hospital East, in Kashiwa, Chiba, Japan discusses this article, "Salvage photodynamic therapy for local failure after chemoradiotherapy for esophageal squamous cell carcinoma." The present study clarified the long-term results and prognostic factors of salvage photodynamic therapy (PDT) for local failure …
Continue reading Photodynamic therapy after CRT for esophageal cancer
Ryan Law, DO¹ and Sachin Wani, MD² discuss their article "Endoscopic resection is cost-effective compared with laparoscopic resection in the management of complex colon polyps: an economic analysis." We performed a cost-effectiveness analysis comparing laparoscopic and endoscopic resection strategies in patients with complex colon polyps and sought to identify predictors that determine cost-effectiveness. Mounting evidence …
Toshio Uraoka, MD, PhD, from the Department of Gastroenterology, National Hospital Organization Tokyo Medical Center, in Tokyo, Japan discusses this New Methods article, "A novel fully synthetic and self-assembled peptide solution for endoscopic submucosal dissection-induced ulcer in the stomach." Application of a novel fully-synthetic and self-assembled peptide solution, which functions as an extracellular matrix scaffold …
Sauid Ishaq, FRCP, from the Department of Gastroenterology, Russells Hall Hospital, Birmingham City University in Birmingham, United Kingdom discusses this systematic review and meta-analysis: "Flexible endoscopic treatment for Zenker's diverticulum: a systematic review and meta-analysis." The aim of this systematic review was to pool the results of endoscopic treatment of Zenker's diverticulum (ZD) in terms …
Tae Young Park, MD¹ and Tae Jun Song, MD, PhD² report their study "Outcomes of ERCP in Billroth II gastrectomy patients." We investigated the outcomes and risk factors for adverse events for endoscopic retrograde cholangiopancreatography (ERCP) using a cap-fitted forward-viewing endoscope with endoscopic papillary balloon dilation (EPBD) in Billroth II gastrectomy patients. ERCP is difficult …
GIE Associate Editor Dr. Doug Adler highlights this article from the June issue: "American Gastroenterological Association guidelines are inaccurate in detecting pancreatic cysts with advanced neoplasia: clinicopathologic study of 225 patients with supporting molecular data." The study is a clear rebuttal of the much-read, much-discussed, and highly controversial AGA guideline on pancreatic cysts, demonstrating the …
Vivek Kumbhari, MD, from the Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, in Baltimore, Maryland, USA discusses this Original Article "Algorithm for the management of ERCP-related perforations." The focus of this study was to assess patient outcomes using a predetermined algorithm based on managing ERCP-related duodenal perforations according to the …
Nathan Gluck, MD, PhD, from the Tel Aviv Medical Center, Research Center for Digestive Disorders and Liver Diseases, in Tel Aviv, Israel discusses this Open Access Original Article "A novel self-propelled disposable colonoscope is effective for colonoscopy in humans (with video)." The focus of this study was to test the cecal intubation rate, safety, and …
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