Post written by Kayla M. Hartz, DO, from the Penn State Hershey Medical Center, Hershey, Pennsylvania.

This case is an example of a successful EUS-guided chemoablation of a patient with a high-risk, main-duct IPMN that was not a surgical candidate. This case highlights that certain high-risk features of pancreatic cysts that would have otherwise been excluded from chemoablation can have successful outcomes when surgery is not an option. Endoscopists should consider chemoablation in patients who would otherwise have been excluded when not candidates for surgery.

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