Editor’s Choice: Impact of mucosal inflammation on risk of colorectal neoplasia

Wallace_headshotGIE Editor-in-Chief, Dr. Michael Wallace, highlights this article from the December issue, “Impact of mucosal inflammation on risk of colorectal neoplasia in patients with ulcerative colitis: a systematic review and meta-analysis” by Brisas M. Flores, MD, et al.

Endoscopy is playing an increasing role in the management of patients with IBD. The special December issue of GIE is dedicated to IBD-related topis. This artilce, by Flores et al, emphasizes the critical role of endoscopy in assessment of inflammation and the impact of chronic inflammation on the development of dysplasia. There is a need to converge the fields of advanced endoscopic imaging and IBD care to achieve optimal care for IBD patients.

We hope this article will further bring together 2 groups of experts, those that take care of IBD patients and those with advanced endoscopic imaging and resection skills. Ongoing, endoscopically detected inflammation increases the risk of colorectal neoplasia. Endoscopists should be familiar with grading systems to describe subtle, sub-clinical inflammation and collaborate with IBD experts to manage that inflamation and subequent neoplasia. The previously published SCENIC guidelines (GIE 2015;81:489-501) provide an excellent resource on detection and management of neoplasia.


Figure 1. Results of the literature search. HIA, histologic inflammatory activity.

Read the article abstract here.

The information presented in Endoscopedia reflects the opinions of the authors and does not represent the position of the American Society for Gastrointestinal Endoscopy (ASGE). ASGE expressly disclaims any warranties or guarantees, expressed or implied, and is not liable for damages of any kind in connection with the material, information, or procedures set forth.

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