Protein biomarkers in pancreatic juice and serum for identification of pancreatic cancer

Post written by Iris J.M. Levink, MD, from the Department of Gastroenterology & Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands. We aimed to develop a panel of biomarkers from serum and pancreatic juice (PJ) to detect pancreatic ductal adenocarcinoma for future surveillance purposes. This study focused on the performance of proteins (interleukin-8 [IL-8]; interferon-γ [IFN-γ]; …

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Improved detection of liver metastasis using Kupffer-phase imaging in contrast-enhanced harmonic EUS in patients with pancreatic cancer

Post written by Kosuke Minaga, MD, PhD, and Masayuki Kitano, MD, PhD, from the Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, and the Second Department of Internal Medicine, Wakayama Medical University School of Medicine, Wakayama, Japan. The focus of this study was to assess the usefulness of Kupffer-phase imaging in contrast-enhanced …

Continue reading Improved detection of liver metastasis using Kupffer-phase imaging in contrast-enhanced harmonic EUS in patients with pancreatic cancer

Permanent endoscopic reversal of Roux-en-Y gastric bypass for diagnosis and long-term palliation of pancreatic cancer

Post written by Seifeldin Hakim, MD, and Phillip S. Ge, MD, from the Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Patients with Roux-en-Y gastric bypass (RYGB) anatomy face unique technical challenges in the management of pancreaticobiliary malignancy. EUS-guided RYGB reversal (known as EDGE or GATE …

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Efficacy of EUS-guided celiac plexus neurolysis compared with medication alone for unresectable pancreatic cancer in the oxycodone/fentanyl era

Post written by Yoshihide Kanno, MD, from the Department of Gastroenterology, Sendai City Medical Center, Miyagi, Japan. The focus of our study was to evaluate the value of routine performance of EUS-guided celiac plexus neurolysis (EUS-CPN) at an early cancer-pain stage. EUS-CPN has been reported to be effective for patients with upper abdominal pain due …

Continue reading Efficacy of EUS-guided celiac plexus neurolysis compared with medication alone for unresectable pancreatic cancer in the oxycodone/fentanyl era

EUS-guided radiofrequency ablation of unresectable pancreatic cancer

Tae Jun Song, MD, PhD, and Dong Wan Seo, MD, PhD, from the Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center in Seoul, South Korea presents this New Methods article, "Initial experience of EUS-guided radiofrequency ablation of unresectable pancreatic cancer." We investigated the feasibility and safety of endoscopic ultrasound (EUS)-guided …

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Editor’s Choice: Outcomes after endoscopic duodenal stent placement for malignant GOO

Associate Editor Fauze Maluf-Filho, MD, PhD, FASGE, highlights this Original Article from the September issue: "Survival and clinical outcome after endoscopic duodenal stent placement for malignant gastric outlet obstruction: comparison of pancreatic cancer and nonpancreatic cancer." The literature supports the concept that patients with malignant gastric outlet obstruction with a predicted survival longer than 3 …

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PGS technology to detect pancreatic cancer

Michael Wallace, MD, MPH from the Department of Gastroenterology and Hepatology at Mayo Clinic in Jacksonville, Florida, USA discusses his article "Polarization gating spectroscopy of normal-appearing duodenal mucosa to detect pancreatic cancer." In this study, we tested the hypothesis that pancreatic cancer is detectable from the normal appearing duodenum, using sophisticated spectroscopy methods. The concept …

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