GIE Senior Associate Editor David L. Diehl, MD, highlights this article from the February issue: “Long-term (3-year) composite gastroesophageal reflux outcomes of peroral endoscopic myotomy with or without concomitant endoscopic fundoplication in matched cohorts of achalasia” by Amol Bapaye, MD (MS), MSGEI, FISG, FASGE, FJGES, et al. To POEM or to POEM + F? In recent years, most …
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Short-term outcomes of endoscopic submucosal dissection for suspected T1 colorectal cancers: a European experience
Post written by Rixta A.H. van Eijck van Heslinga, MD, and Leon M.G. Moons, MD, PhD, from the Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands. The management of colorectal polyps with suspected deep submucosal invasive carcinoma (d-SMIC) remains a subject of ongoing debate. Optical assessment often overestimates the risk of d-SMIC, resulting in unnecessary surgeries for …
Endoscopic approaches to reduce the incidence of interval colon cancer
Post written by Saurabh Chandan, MD, from Houston Methodist West Hospital, Houston, Texas, USA. The primary focus of this study was to review and summarize endoscopic techniques to mitigate and lower the incidence of interval colon cancer, which is defined as a colorectal cancer (CRC) diagnosed after a screening examination or test in which no cancer …
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Evaluating the outcomes and safety of underwater ampullectomy versus traditional (gas insufflation) ampullectomy (with video)
Post written by Anand Kumar, MD, MPH, from Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA. We compared outcomes such as rates of histologic negative margins, procedure times, and recurrence of underwater ampullectomy (UA) with traditional (gas insufflation) ampullectomy (TA) for polyps involving the ampulla. Underwater resection has proven advantages of higher en bloc resection, lower recurrence, and …
Clinical outcomes of endoscopic ultrasound–guided gallbladder drainage in patients with acute cholecystitis with ≥1 year of follow-up: a systematic review and meta-analysis
Post written by Andrew Canakis, DO, from the Division of Gastroenterology and Hepatology, TidalHealth Peninsula Regional Medical Center, Salisbury, Maryland, USA. The aim of this study was to investigate mid-term clinical outcomes after EUS-guided gallbladder drainage (EUS-GBD), with a focus on clinical success and the rate of recurrent cholecystitis. Although a multitude of studies have demonstrated the …
Best of artificial intelligence in GI endoscopy
Post written by Michael B. Wallace, MD, MPH, from Mayo Clinic Florida, Jacksonville, Florida, USA. This is part of a series of invited reviews focusing on the best articles of the past year. "Best of artificial intelligence in GI endoscopy" allows our endoscopic community to get a rapid overview of the top publications in the field of artificial …
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Safety and feasibility of intensive endoscopic interventions for delayed perforation after colorectal endoscopic submucosal dissection (with video)
Post written by Satoki Shichijo, MD, PhD, from Osaka International Cancer Institute, Osaka, Japan. Endoscopic submucosal dissection (ESD) was performed for 1763 patients with 1845 lesions (right-sided colon, 1018; left-sided colon, 827) between February 2011 and April 2023. Thirty-two delayed perforations (26 between 2011 and 2020; 6 between 2021 and 2023) occurred. Muscle injury occurred during ESD …
EMR versus surgery for colon adenomas and early-stage cancers: a comparative effectiveness study
Post written by Karl Kwok, MD, FASGE, and Andrew Giap, MD, FASGE, from the Southern California Permanente Medical Group, and Brian Lim, MD, FASGE, from United Medical Doctors, Irvine, and the University of California, Riverside, School of Medicine, Riverside, California, USA. Interventional endoscopists have known the advantages of EMR for many years. However, published EMR data in a large, community-based multispecialty …
The best of EUS in 2025
Post written by GIE Senior Associate Editor David L. Diehl, MD, MASGE, AGAF, from the Department of Gastroenterology and Hepatology, Geisinger Medical Center, Danville, Pennsylvania, USA. I sat down to write an Endoscopedia post on my recently published article, “The best of EUS in 2025.” I got about 500 words in, then decided to scrap that approach. …
Local recurrence rates of horizontal margin-positive en bloc endoscopic submucosal dissection of colorectal neoplasia: a meta-analysis
Post written by Daan A. Verhoeven, BSc, and Hao Dang, MD, PhD, from Leiden University Medical Center, Leiden, The Netherlands. In this meta‑analysis, we set out to evaluate how often local recurrence occurs following en bloc endoscopic submucosal dissection (ESD) of colorectal neoplasia when the horizontal margin is positive or indeterminate. We compared that risk to cases with a negative horizontal margin …
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