Molecular cytology genotyping of primary and metastatic GI stromal tumors

Post written by Ferga C. Gleeson, MD, from the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. In patients with either primary or metastatic sporadic GI stromal tumors, we sought to determine the frequency of KIT and PDGFRA pathogenic alterations within paired endoscopic ultrasound cytology smears and surgical pathology specimens, Imatinib sensitivity, and the …

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