The open accordion: a novel application of endoscopic sleeve gastroplasty for the treatment of refractory gastroparesis

Post written by Alexander J. Podboy, MD, from the University of Virginia, Charlottesville, Virginia, USA. Gastroparesis is a debilitating condition that leads to poor quality of life. Although gastric peroral endoscopic myotomy (G-POEM) has emerged as a novel treatment, its success rates are variable, and options for patients with refractory symptoms remain limited. This video case introduces …

Continue reading The open accordion: a novel application of endoscopic sleeve gastroplasty for the treatment of refractory gastroparesis

Long-term outcomes (≥3 years) after gastric peroral endoscopic myotomy for refractory gastroparesis: a systematic review and meta-analysis

Post written by Andrew Canakis, DO, from the Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, Maryland, USA. Refractory gastroparesis is a chronic debilitating condition that results in decreased quality of life, weight loss/malnutrition, and increased healthcare costs. Medical options with prokinetic agents are often limited, and intrapyloric botulinum toxin injection has …

Continue reading Long-term outcomes (≥3 years) after gastric peroral endoscopic myotomy for refractory gastroparesis: a systematic review and meta-analysis

Gastric peroral endoscopic myotomy for management of refractory gastroparesis in patients with gastric neurostimulator devices: a multicenter retrospective case control study

Post written by Cyrus R. Piraka, MD, FASGE, from the Henry Ford Health System, Detroit, Michigan, USA. This study explores whether gastric peroral endoscopic myotomy (G-POEM) could serve as salvage therapy for refractory gastroparesis in patients who had a gastric neurostimulator (GNS) implanted. It was designed as a multicenter, retrospective, 1:2-matched case-control study comparing outcomes …

Continue reading Gastric peroral endoscopic myotomy for management of refractory gastroparesis in patients with gastric neurostimulator devices: a multicenter retrospective case control study

Gastric peroral endoscopic myotomy for the treatment of refractory gastroparesis

Post written by Mohammad Al-Haddad, MD, from the Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA. The study focused on prospectively assessing the safety and efficacy of gastric peroral endoscopic myotomy in improving symptoms, quality of life, and healthcare resource utilization in a cohort of gastroparesis patient that had failed …

Continue reading Gastric peroral endoscopic myotomy for the treatment of refractory gastroparesis

Gastric peroral endoscopic myotomy for refractory gastroparesis

Post written by Shaimaa Elkholy, MD, from the Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt. We present here a case of a middle-aged male patient with history of refractory gastroparesis post-surgical fundoplication. Despite using extensive medical treatment of antiemetics and prokinetics, his condition was deteriorating. We performed G-POEM, which is …

Continue reading Gastric peroral endoscopic myotomy for refractory gastroparesis

Short-term outcomes of double versus single pyloromyotomy at peroral endoscopic pyloromyotomy in the treatment of gastroparesis

Post written by Qiang Cai, MD, PhD, from the Emory University School of Medicine, Division of Digestive Diseases, Atlanta, Georgia, USA. The focus of our study was to compare the short-term outcomes of double myotomy versus single myotomy at peroral endoscopic pyloromytomy in the treatment of gastroparesis. Peroral endoscopic pyloromytomy (POP or GPOEM) is a …

Continue reading Short-term outcomes of double versus single pyloromyotomy at peroral endoscopic pyloromyotomy in the treatment of gastroparesis

Duration or etiology of gastroparesis and clinical response after gastric per-oral endoscopic pyloromyotomy

Post written by Parit Mekaroonkamol, MD, Vaishali Patel, MD, MHS, and Qiang Cai, MD, PhD, from the Emory University School of Medicine, Atlanta, Georgia, and the King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand. Gastric per-oral endoscopic pyloromyotomy (GPOEM) is an emerging endoscopic procedure for treatment of gastroparesis. Although multiple studies have demonstrated impressive clinical …

Continue reading Duration or etiology of gastroparesis and clinical response after gastric per-oral endoscopic pyloromyotomy

Endoscopic aspects of temporary gastric electrical stimulator lead placement

Post written by Minesh Mehta, MD, and Gregg Wendorf, MD, from the Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, University of Louisville, Louisville, Kentucky, USA. Our video details the technique and tools required to successfully and safely place temporary gastric electrodes endoscopically, even in the presence of retained gastric contents. Gastric electrical stimulation …

Continue reading Endoscopic aspects of temporary gastric electrical stimulator lead placement

Outcomes and quality-of-life assessment after GPOEM

Post written by Parit Mekaroonkamol, MD, Sunil Dacha, MD, and Qiang Cai, MD, PhD, from Emory University School of Medicine. Gastric per-oral endoscopic pyloromyotomy (GPOEM) is an emerging endoscopic procedure for treatment of gastroparesis. Due to its novelty, the existing data on its safety and efficacy is lacking. The purpose of our study was to …

Continue reading Outcomes and quality-of-life assessment after GPOEM

Gastric endoscopic muscle biopsy

Elizabeth Rajan, MD, FASGE from the Mayo Clinic College of Medicine in Rochester, Minnesota, USA describes this New Methods article "Innovative gastric endoscopic muscle biopsy to identify all cell types, including myenteric neurons and interstitial cells of Cajal in patients with idiopathic gastroparesis: a feasibility study (with video)." The pathophysiology of some gastrointestinal neuromuscular diseases …

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