Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver

Post written by Robert L. Kruse, MD, PhD, from the Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Viral-based approaches predominate the field of gene therapy for rare diseases but suffer many limitations including anti-vector immune responses and high cost of manufacturing. Our study focused on developing a novel nonviral …

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Extracorporeal rendezvous technique combining endoscopic retrograde pancreatography with endoscopic ultrasound for main pancreatic duct disconnection arising from acute necrotizing pancreatitis

Post written by Toshiyasu Shiratori, MD, from the Department of Gastroenterology, Kameda Medical Center, Kamogawa City, Japan. This video shows an endoscopic pancreatic duct drainage technique combining ERCP with EUS using a percutaneous drainage route for main pancreatic duct disconnection that was difficult to traverse through the disconnected segment using either ERCP- or EUS-guided approaches. …

Continue reading Extracorporeal rendezvous technique combining endoscopic retrograde pancreatography with endoscopic ultrasound for main pancreatic duct disconnection arising from acute necrotizing pancreatitis

Trends in performance of ERCP among patients with surgically unresectable pancreatic cancer

Post written by Patrick Yachimski, MD, MPH, from the Division of Gastroenterology, Hepatology & Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA. This study was conducted to assess whether there has been a change over time in the use of ERCP among patients with surgically unresectable pancreas cancer, and if so, if there was any …

Continue reading Trends in performance of ERCP among patients with surgically unresectable pancreatic cancer

Disposable digital percutaneous cholangioscope-aided retrieval of a plastic biliary stent after failed retrieval at ERCP

Post written by Sooraj Tejaswi, MD, MSPH, from the Division of Gastroenterology & Hepatology, University of California Davis School of Medicine, Sacramento, California. We describe the collaborative effort of the use of the novel short cholangioscope-aided percutaneous retrieval of a plastic biliary stent after being unable to retrieve the stent during ERCP. The patient was …

Continue reading Disposable digital percutaneous cholangioscope-aided retrieval of a plastic biliary stent after failed retrieval at ERCP

Nonsurgical rescue after basket-stone impaction by endoscopic cutting of a metallic lithotripter and laser lithotripsy

Post written by Toshiaki Terauchi, MD, from the Department of Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Japan. This report presents a 64-year-old male who underwent successful rescue using a nonsurgical endoscopic approach to remove an impacted mechanical lithotripter basket, due to a 17-mm common bile duct stone. The basket impaction occurred at an outside hospital, and …

Continue reading Nonsurgical rescue after basket-stone impaction by endoscopic cutting of a metallic lithotripter and laser lithotripsy

Double high-level disinfection versus liquid chemical sterilization for reprocessing of duodenoscopes used for ERCP

Post written by Mark A. Gromski, MD, from the Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA. This study aimed to answer whether there were any differences in 2 different duodenoscope reprocessing methods that fulfilled supplemental measures to enhance reprocessing: double high-level disinfection and liquid chemical sterilization. …

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EUS-guided jejunojejunostomy to facilitate ERCP in a patient with unique Roux-en-Y gastric bypass anatomy

Post written by Ryan Law, DO, from the University of Michigan, Ann Arbor, Michigan. In our case presentation we describe a patient who presented to our institution with concern for biliary pathology in the setting of prior Roux-en-Y gastric bypass with an indwelling percutaneous biliary drain. Importantly, this patient underwent a sleeve gastrectomy prior to …

Continue reading EUS-guided jejunojejunostomy to facilitate ERCP in a patient with unique Roux-en-Y gastric bypass anatomy

Bilateral balloon expandable biodegradable stent (Y-stent) for postcholecystectomy perihilar biliary stricture

Post written by Sundeep Lakhtakia, MD, DM, and Harsh Vardhan Tevethia, MD, DM, from the Department of Medical Gastroenterology, AIG Hospitals and Asian Institute of Gastroenterology, Hyderabad, Telangana, India. Following complicated laparoscopic cholecystectomy, a young woman developed a biliary stricture that required several ERCP sessions. She presented with recurrent jaundice. MRCP revealed a perihilar stricture …

Continue reading Bilateral balloon expandable biodegradable stent (Y-stent) for postcholecystectomy perihilar biliary stricture

EUS-guided choledochoduodenostomy as a rescue after failed ERCP and percutaneous transhepatic biliary drainage in the management of postoperative benign biliary stricture

Post written by Sundeep Lakhtakia, MD, MNAMS, DM, FASGE, from the Department of Medical Gastroenterology, AIG Hospitals and Asian Institute of Gastroenterology, Hyderabad, Telangana, India. A young woman who had surgical choledocho-duodenostomy 5 years ago for biliary adverse events soon after cholecystectomy presented with biliary obstruction. MRCP revealed a smooth mid-CBD stricture, intra-hepatic stone with …

Continue reading EUS-guided choledochoduodenostomy as a rescue after failed ERCP and percutaneous transhepatic biliary drainage in the management of postoperative benign biliary stricture

Early precut versus primary precut sphincterotomy to reduce post-ERCP pancreatitis

Post written by Sudhir Maharshi, MD, DM, and Shyam Sunder Sharma, DNB, DM, from the Department of Gastroenterology, SMS Medical College and Hospitals, Jaipur, India. The focus of our study was to assess the safety and efficacy of primary precut. It is well known that precut sphincterotomy, usually considered after repeated and failed cannulation, is …

Continue reading Early precut versus primary precut sphincterotomy to reduce post-ERCP pancreatitis