Successful hemostasis of active lower GI bleeding using a hemostatic powder as mono-, combination, or rescue therapy

Post written by Lawrence Hookey, MD, from the Hotel Dieu Hospital, Kingston, Ontario, Canada. This study is the largest to prospectively evaluate the hemostatic powder TC-325 in lower GI bleeding. We included 50 patients with bleeding from different sources, and performed extensive efficacy and safety follow-up. TC-325 is a newer product (having just received regulatory …

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Editor’s Choice: GEA vs MAC in high-risk patients undergoing ERCP

GIE Associate Editor, Dr. Sharmila Anandasabapathy, highlights this article from the April issue “A randomized controlled trial evaluating general endotracheal anesthesia versus monitored anesthesia care and the incidence of sedation-related adverse events during ERCP in high-risk patients” by Zachary L. Smith, DO, et al.  This is one of the few studies which compare, via a randomized …

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Clinical and endoscopic predictors for intraprocedural mucosal injury during per-oral endoscopic myotomy

Post written by Ping-Hong Zhou, MD, PhD, from the Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China. We aimed to explore the characteristics, predictors, and management approaches of intraprocedural mucosal injury. As the mucosal flap is the only barrier between the mediastinum and esophageal lumen during per-oral endoscopic myotomy (POEM), mucosal …

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Conscious transnasal hybrid ESD enables safe and painless en bloc resection

Post written by Yohei Minato, MD, from the NTT Medical Center, Tokyo, Japan. With the transnasal endoscopy, we successfully performed hybrid endoscopic submucosal dissection (ESD) of an early gastric cancer without sedation. Endoscopic Submucosal Dissection (ESD) is a technically demanding and time-consuming procedure, which is usually performed under sedation. Recently, hybrid ESD was developed as …

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Endoscopic sleeve gastroplasty versus laparoscopic sleeve gastrectomy

Post written by Vivek Kumbhari, MD, and Lea Fayad, MD, from the Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA. Our study compared 2 weight-loss procedures, the commonly performed laparoscopic sleeve gastrectomy (LSG) and the newly introduced, minimally invasive endoscopic sleeve gastroplasty (ESG). The LSG has excellent weight-loss outcomes but, as an elective …

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Endoclip-assisted giant colon lipoma resection

Post written by Shou-jiang Tang, MD, from the Division of Digestive Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA. We reported a case of a symptomatic giant sigmoid colon lipoma (7 cm × 6 cm) that was successfully removed with endoclip assisted dissection. Considering its size, thick stalk, and the possibility …

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Efficacy of 3 fine-needle biopsy techniques for suspected pancreatic malignancies

Post written by Tae Hoon Lee, MD, PhD, from the Department of Internal Medicine, SoonChunHyang University School of Medicine, Cheonan, Korea. EUS-guided fine-needle aspiration/biopsy (EUS-FNA/B) has a high diagnostic accuracy for pancreatic tumors. However, the ability of various FNA/B techniques to obtain an adequate mass of cells or tissue has rarely been investigated, especially in …

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Bouveret syndrome: a tough nut to crack

Post written by Ijlal Akbar Ali, MD, from the Department of Digestive Diseases and Nutrition, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA. We describe a case of a morbidly obese woman who presented to the emergency room with a 3-day history of right upper-quadrant abdominal pain. CT scan obtained demonstrated a 3-cm gallstone …

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Endoscopic full-thickness resection of a gastric GI stromal tumor

Post written by Vincent Huberty, MD, from the Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium. This is a video case report of a 76-year-old woman diagnosed with a 23-mm gastric GIST located in the fundus, on the greater curvature. Workup (including fine-needle aspiration, bite-to-bite biopsies, and EUS) …

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Comparing adenoma and polyp miss rates for total underwater colonoscopy versus standard CO2

Post written by Joseph C. Anderson, MD, MHCDS, from the Department of Veterans Affairs Medical Center, White River Junction, Vermont, and the Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. The purpose of this study was to compare water to standard CO2 as a medium to inspect the colonic mucosa for polyp detection. …

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