Post written by Daan A. Verhoeven, BSc, and Hao Dang, MD, PhD, from Leiden University Medical Center, Leiden, The Netherlands. In this meta‑analysis, we set out to evaluate how often local recurrence occurs following en bloc endoscopic submucosal dissection (ESD) of colorectal neoplasia when the horizontal margin is positive or indeterminate. We compared that risk to cases with a negative horizontal margin …
Category: Investigations
Burden and cost of post–endoscopic retrograde cholangiopancreatography pancreatitis among commercially insured people undergoing endoscopic retrograde cholangiopancreatography
Post written by Anna Tavakkoli, MD, from the University of Texas Southwestern, Dallas, Texas, USA. Endoscopic retrograde cholangiopancreatography (ERCP) is the primary therapeutic procedure for a number of pancreaticobiliary diseases. The most common adverse event associated with ERCP is post-ERCP pancreatitis (PEP). Studies estimate that PEP can occur in 10% to 15% of patients, and …
Revisiting the starting age of colorectal cancer screening for the average-risk Asian population: a cost-effectiveness analysis
Post written by Martin C.S. Wong, MD, and Junjie Huang, PhD, from The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong. The incidence and mortality of early-onset colorectal cancer (CRC) have been increasing in many parts of the world. The American Cancer Society and the U.S. …
Predicting the need for step-up after EUS-guided drainage of peripancreatic fluid collections, including Quadrant-Necrosis-Infection score validation: a prospective cohort study
Post written by Giuseppe Vanella, MD, PhD, from San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy. When dealing with symptomatic or infected peripancreatic fluid collections (PFCs), EUS-guided drainage has become the standard of care. In about one-half of cases, drainage alone will be enough to solve the issue. Yet, a fraction of patients will require further …
Risk of post–endoscopic retrograde cholangiopancreatography pancreatitis due to placement of biliary self-expandable metal stents: a single-center retrospective study
Post written by Bashar Qumseya, MD, MPH, FASGE, from the University of Florida, Gainesville, Florida, USA. This study focuses on the risk of post-ERCP pancreatitis (PEP) in patients who receive self-expandable metal stents (SEMSs) compared with plastic biliary stents at the time of ERCP. We observed several patients who underwent PEP with seemingly no other …
Randomized crossover trial comparing through-the-scope balloon enteroscopy via colonoscope with standard colonoscopy on depth of ileal insertion
Post written by M. Ammar Kalas, MD, from Texas Tech University Health Sciences Center El Paso, El Paso, Texas, USA. This study aimed to assess the effect of a through-the-scope balloon attachment on depth of maximal ileal insertion (DMI) during retrograde enteroscopy. We adopted a crossover trial design in which each patient in the study …
Endoscopic suturing to prevent migration of esophageal fully covered self-expandable metal stents: a randomized controlled trial (with video)
Post written by Shailendra Singh, MD, from West Virginia University, Morgantown, West Virginia, USA. Fully covered self-expandable metal stents (FC-SEMSs) are widely used in the management of both benign and malignant esophageal disorders, including strictures, leaks, and perforations. However, high migration rates—often exceeding 30% to 60%—remain a major limitation of their use, leading to recurrent …
Physical recovery after local resection of nonpedunculated rectal adenomas and T1 carcinomas: endoscopic submucosal dissection versus transanal minimally invasive surgery
Post written by Nik Dekkers, MD, from Leiden University Medical Center, Leiden, The Netherlands. The focus of our study was to quantitatively assess physical recovery after endoscopic submucosal dissection (ESD) and transanal minimally invasive surgery (TAMIS) for large rectal lesions. We used wearable accelerometers (smartwatches) to objectively measure physical activity and to investigate key factors influencing recovery. We …
Safety and efficacy of EUS-guided pelvic abscess drainage with lumen-apposing metal stents for complicated acute diverticulitis
Post written by Andrea Lisotti, MD, from the Gastroenterology Unit, Hospital of Imola, University of Bologna, Italy, and the Gastroenterology Unit, Hôpital Privé Jean Mermoz, Lyon, France. Our study evaluated the safety and efficacy of endoscopic ultrasound—guided pelvic abscess drainage (EUS-PAD) using lumen-apposing metal stents in patients with complicated acute diverticulitis. This minimally invasive approach …
Optical enhancement with magnification versus white-light endoscopy for detecting gastric intestinal metaplasia and neoplasia: a randomized controlled trial
Post written by Zhen Li, MD, from the Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, China. We conducted a randomized controlled trial comparing optical enhancement combined with magnification endoscopy (ME-OE) with conventional white-light endoscopy (WLE) for detection of gastric intestinal metaplasia (GIM), gastric intraepithelial neoplasia (GIN), and early gastric cancer (EGC). Detection of …
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