Post written by Roberto de Sire, MD, PhD, from the Endoscopy Unit, Gastroenterology Department, Humanitas Research Hospital IRCCS, Rozzano, and the IBD Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy. Our study explored a timely and practical question in therapeutic endoscopy: among the newer endoscopic submucosal dissection (ESD) strategies developed for colorectal lesions, …
Category: Investigations
Optimal number of needle passes in endoscopic ultrasound–guided tissue sampling for genomic profiling: a randomized, noncomparative trial
Post written by Hirotoshi Ishiwatari, MD, PhD, from the Department of Pancreatobiliary Medicine, Shizuoka Cancer Center, Shizuoka, Japan. The study aimed to investigate the optimal techniques for EUS-guided tissue acquisition (EUS-TA) to achieve successful comprehensive genomic profiling (CGP) testing using commercially available assays. Matched therapy based on commercially available CGP tests plays a crucial role in improving …
Clinical characteristics analysis of anorectal function changes after endoscopic submucosal dissection for rectal lesions
Post written by Pin Wang, MM, from The First Affiliated Hospital of Nanjing Medical University and Nanjing Mei Shan Hospital and Bixing Ye, MD, Guoxin Zhang, MD, Lin Lin, MD, and Liuqin Jiang, MD, from The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. This study systematically evaluates anorectal function changes following endoscopic submucosal dissection (ESD) for rectal lesions. We assessed incidence, characteristics, and temporal patterns of postoperative …
Prophylactic clipping versus no clipping after endoscopic mucosal resection of large nonpedunculated colon polyps: a cost-effectiveness analysis
Post written by Sneh Sonaiya, MD, from the Department of Internal Medicine, University of Nevada Las Vegas, Las Vegas, Nevada, and Babu P. Mohan, MD, from the University of Central Florida School of Medicine and Orlando Gastroenterology PA, Orlando, Florida, USA. Although prophylactic clipping is commonly used after EMR of large colon polyps to reduce delayed postpolypectomy bleeding, its cost-effectiveness …
Clinical outcomes of endoscopic submucosal dissection for residual neoplasia after incomplete resection of large nonpedunculated colorectal polyps: a large multicenter propensity match study (with video)
Post written by Ernesto Robalino Gonzaga, MD, from Gastroenterology and Hepatology, AdventHealth Medical Group, and Dennis Yang, MD, from the Center for Interventional Endoscopy, AdventHealth, Orlando, Florida, USA. Our study evaluated the clinical outcomes of endoscopic submucosal dissection (ESD) for residual neoplasia after incomplete endoscopic resection of large nonpedunculated colorectal polyps. Specifically, we compared outcomes of ESD performed as salvage …
Clinical impact of routine esophagram after peroral endoscopic myotomy: a systematic review and meta-analysis
Post written by Ernesto Robalino Gonzaga, MD, from the University of Pennsylvania, Philadelphia, Pennsylvania, and Gastroenterology, AdventHealth Medical Group, Orlando, Florida, Saurabh Chandan, MD, from Houston Methodist West Hospital, Houston, Texas, USA, and the Center for Interventional Endoscopy, AdventHealth, and Dennis Yang, MD, from the Center for Interventional Endoscopy, AdventHealth. Our study evaluates whether a routine esophagram after peroral endoscopic myotomy (POEM) …
Clinical impact of combination of lesion-border findings and pit patterns for identifying invasive versus noninvasive neoplastic lesions in ulcerative colitis
Post written by Yurie Kawabata, MD, from Digestive Disease Center, Showa Medical University Northern Yokohama Hospital, Yokohama, Japan. Our study focuses on evaluating whether assessing lesion-border findings (“distinct” vs “indistinct” borders) using indigo carmine chromoendoscopy can help identify cases in which Kudo’s pit pattern analysis is truly reliable for predicting the invasion depth of lesions in patients …
Postprocedural cholecystitis following covered self-expandable metal stent placement in patients with distal malignant biliary obstruction: a systematic review and meta-analysis
Post written by Chawin Lopimpisuth, MD, from the Department of Medicine, University of Miami/Jackson Health System, Miami, Florida, and Sean Bhalla, MD, from the Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Denver, Colorado, USA. This study aimed to compare the safety of covered self-expandable metal stents (CSEMSs) versus uncovered self-expandable metal stents (USEMs) in the management …
Long-term (3-year) composite gastroesophageal reflux outcomes of peroral endoscopic myotomy with or without concomitant endoscopic fundoplication in matched cohorts of achalasia
Post written by Amol Bapaye, MD (MS), MSGEI, FISG, FASGE, FJGES, from Shivanand Desai Center for Digestive Disorders, Deenanath Mangeshkar Hospital and Research Center, Pune, India. The objective of this study was to perform a retrospective comparison of long-term (3-year) gastroesophageal reflux (GER) rates in a matched cohort of patients with achalasia cardia who underwent only peroral …
Short-term outcomes of endoscopic submucosal dissection for suspected T1 colorectal cancers: a European experience
Post written by Rixta A.H. van Eijck van Heslinga, MD, and Leon M.G. Moons, MD, PhD, from the Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands. The management of colorectal polyps with suspected deep submucosal invasive carcinoma (d-SMIC) remains a subject of ongoing debate. Optical assessment often overestimates the risk of d-SMIC, resulting in unnecessary surgeries for …
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