Post written by Edward J. Despott, MD, FRCP, FEBGH, FASGE, MD(Res), from the Royal Free Unit for Endoscopy, The Royal Free Hospital and University College London (UCL) Institute for Liver and Digestive Health, Hampstead, London, United Kingdom.

This short video demonstrates the usefulness of loop ligation facilitated by double-balloon enteroscopy (DBE) for endotherapy of gastrointestinal (GI) vascular lesions caused by blue rubber bleb nevus syndrome (BRBNS). The video gives a direct endoscopic representation of the findings in such cases, and also demonstrates the technique of loop ligation for endotherapy of these lesions in this rare condition.

The key take-home message of this video is that loop ligation of vascular GI lesions caused by BRBNS is a simple and safe modality for the management of such lesions, which are often the culprit of transfusion-dependent anemia in affected patients. This effective technique, avoids the potential risks of other alternative types of endotherapy (such as sclerotherapy and resection).

Our video describes and demonstrates this simple and effective technique and highlights the importance of safety, which may be more of an issue with alternative methods of endotherapy for GI lesions associated with BRBNS.

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