Closure of gastric mucosal defects using the reopenable-clip over-the-line method to decrease the risk of bleeding after endoscopic submucosal dissection: a multicenter propensity score–matched case-control study (with video)

Post written by Tatsuma Nomura, MD, from the Department of Gastroenterology, Suzuka General Hospital, Suzuka, and Shinya Sugimoto, MD, from the Department of Gastroenterology, Ise Red Cross Hospital, Ise, Japan. A retrospective study was conducted to analyze endoscopic submucosal dissection (ESD) procedures performed between January 2012 and March 2024. Patients were classified into 2 groups: a nonclosure group, where …

Continue reading Closure of gastric mucosal defects using the reopenable-clip over-the-line method to decrease the risk of bleeding after endoscopic submucosal dissection: a multicenter propensity score–matched case-control study (with video)

Quadrant, necrosis, and infection criteria for the risk stratification of walled-off necrosis: external validation using multi-institutional data

Post written by Hideyuki Shiomi, MD, PhD, from the Division of Hepatobiliary and Pancreatic Diseases, Department of Gastroenterology, Hyogo Medical University, Hyogo, and Tomotaka Saito, MD, PhD, from the Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan, for the WONDERFUL study group. Our study externally validated the quadrant (an abdominal quadrant distribution), necrosis, and infection (QNI) …

Continue reading Quadrant, necrosis, and infection criteria for the risk stratification of walled-off necrosis: external validation using multi-institutional data

Radiofrequency vapor ablation for duodenal mucosal ablation in the treatment of type 2 diabetes: results from the first-in-human pilot study

Post written by Benjamin Norton, MD, from Cleveland Clinic London, London, United Kingdom. We are currently experiencing an obesity and diabetic epidemic. We know that the number of people living with type 2 diabetes (T2D) is expected to rise worldwide to alarming rates (1.31 billion by 2050).1 We are seeing an explosion in the number …

Continue reading Radiofrequency vapor ablation for duodenal mucosal ablation in the treatment of type 2 diabetes: results from the first-in-human pilot study

Saline immersion endoscopic submucosal dissection for management of early Barrett’s esophagus adenocarcinoma and large esophageal varices

Post written by Giuliano Francesco Bonura, MD, from the Gastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, Carpi, Italy. A 65-year-old man was referred to our unit with long-segment Barrett’s esophagus (Prague C6, M10) with 2 bulky adjacent sessile lesions (30 mm and 15 mm) positive for adenocarcinoma at biopsies. Magnification endoscopy with narrow-band imaging …

Continue reading Saline immersion endoscopic submucosal dissection for management of early Barrett’s esophagus adenocarcinoma and large esophageal varices

Improvement in obesity-related comorbidities 5 years after endoscopic sleeve gastroplasty: a prospective cohort study

Post written by Ali Lahooti, MD, and Reem Z. Sharaiha, MD, MSc, from the Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA. Our study aimed to prospectively evaluate the long-term effectiveness of endoscopic sleeve gastroplasty (ESG) as a standalone therapy for treating obesity and its related comorbidities over a period of …

Continue reading Improvement in obesity-related comorbidities 5 years after endoscopic sleeve gastroplasty: a prospective cohort study

A lifetime of pushing boundaries: thinking outside the box to endoscopically treat complex gastrointestinal diseases

Post written by Todd H. Baron, MD, MASGE, from the University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA, and Phillip S. Ge, MD, FASGE, from the University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Please join iGIE in celebrating the career of Dr Todd Baron, a legendary pioneer who dared to break rules to …

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Hybrid endoscopic submucosal dissection and endoscopic full-thickness resection for R0 resection of T1 colonic adenocarcinoma

Post written by Rahul Karna, MD, from the University of Minnesota, Minneapolis, Minnesota, USA, and Mohammad Bilal, MD, from the University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA. In this case, we describe management of a 35-mm malignant colon polyp in a patient at high risk for surgery. Colonoscopic exam revealed a nonpolypoid lesion (Paris classification IIa+IIc) in the …

Continue reading Hybrid endoscopic submucosal dissection and endoscopic full-thickness resection for R0 resection of T1 colonic adenocarcinoma

Management of ERCP-related perforation: a large multicenter study

Post written by Tomoya Emori, MD, PhD, from Wakayama Rosai Hospital, Wakayama, Japan. This study retrospectively evaluated the characteristics and clinical outcomes of patients with ERCP-related duodenal perforations according to the mechanism of injury. Perforation is a rare but serious adverse event associated with ERCP. There is no consensus to guide clinicians in the management of ERCP-related …

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Coagulation forceps-sparing techniques for pre-emptive sealing of blood vessels during third-space endoscopy

Post written by Zaheer Nabi, MD, DNB, FASGE, FISG, FSGEI, from the Asian Institute of Gastroenterology, Hyderabad, India. This video presents a series of coagulation forceps-sparing techniques used during third-space endoscopy, including peroral endoscopic myotomy. Using various electrosurgical knife-based and bipolar coagulation methods, we demonstrate how large blood vessels encountered during submucosal dissection can be …

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Cold- versus hot-snare endoscopic mucosal resection of colorectal polyps: meta-analysis of randomized controlled trials

Post written by Aamir Saeed, MD, from Vanderbilt University Medical Center, Nashville, Tennessee, USA. We aimed to conduct a meta-analysis of randomized controlled trials (RCTs) to compare cold EMR versus hot EMR for colorectal polyps. Interest in cold EMR for colorectal polyps has been growing, and cold EMR has gained popularity owing to its lower risk of …

Continue reading Cold- versus hot-snare endoscopic mucosal resection of colorectal polyps: meta-analysis of randomized controlled trials