Post written by Raymond E. Kim, MD, from the University of Maryland School of Medicine, Baltimore, MD, USA. The primary focus of our study was to compare the difficulty and success rate of peroral endoscopic myotomy (POEM) in treatment-naïve cases versus treatment-refractory patients with esophageal motility disorders. There is a prevailing belief that treatment-refractory cases, which …
Category: Investigations
Prospective multicenter assessment of the impact of EUS-guided gastroenterostomy on patient quality of life in unresectable malignant gastric outlet obstruction
Post written by Manuel Pérez-Miranda, MD, PhD, from the Gastroenterology Department, Hospital Universitario Río Hortega, Valladolid, Spain. Our study focuses on the short-term impact of EUS-guided gastroenterostomy (EUS-GE) on quality of life (QoL) in patients with malignant gastric outlet obstruction (GOO). Available EUS-GE case series rely on the achievement of a full diet or reintervention rates …
Exposed versus nonexposed endoscopic full-thickness resection for duodenal subepithelial lesions: a tertiary care center experience (with videos)
Post written by Zaheer Nabi, MD, DNB, from the Asian Institute of Gastroenterology, Hyderabad, India. In this study, the feasibility and safety of exposed versus nonexposed endoscopic full-thickness resection (EFTR) in patients with large (≥10 mm) duodenal subepithelial lesions were evaluated. Exposed EFTR was performed using a conventional electrosurgical knife, and the ensuing full-thickness defect was …
Diagnostic yield of random colon biopsy sampling in patients with chronic diarrhea and normal colonoscopy: a systematic review and meta-analysis
Post written by Priyadarshini Loganathan, MD, from University Medical Associates, University of Texas Health Science Center, San Antonio, Texas, USA. The focus of our study was to identify the pooled diagnostic value of random colonic biopsy sampling in patients with chronic nonbloody diarrhea and a normal colonoscopy examination. There is a need to quantify the pooled …
Long-term outcomes of local resection versus surgical resection for high-risk T1 colorectal cancer: a systematic review and meta-analysis
Post written by Yuxiang Chen, MM, and Kai Deng, MD, from the Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, and Sichuan University–Oxford University Huaxi Gastrointestinal Cancer Centre, Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, China. Our study was performed as a systematic retrieval of data from existing studies and pooled …
Risk of post-sphincterotomy bleeding with antiplatelet and anticoagulant use: a propensity-matched analysis of the U.S. Collaborative Network
Post written by Saurabh Chandan, MD, from Creighton University School of Medicine, Omaha, Nebraska, USA. The main focus of our study was to assess the outcomes of ERCP with sphincterotomy among patients on anticoagulant (AC) and antiplatelet (APT) agents. We performed a retrospective analysis using the TriNetX database, which is a global, federated research network providing …
EUS-guided fine-needle biopsy sampling of solid pancreatic tumors with 3 versus 12 to-and-fro movements: a multicenter prospective randomized controlled study
Post written by Kosuke Takahashi, MD, PhD, from the Department of Gastroenterology and Hepatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, and Ichiro Yasuda, MD, PhD, from the Third Department of Internal Medicine, University of Toyama, Toyama, Japan. In this study, a novel EUS-guided fine-needle biopsy sampling (EUS-FNB) needle enabled physicians to obtain sufficient …
Detection and endoscopic classification of intraductal neoplasms of the bile duct by peroral cholangioscopy with narrow-band imaging (with videos)
Post written by Il Sang Shin, MD, PhD, Jong Ho Moon, MD, PhD, and Yun Nah Lee, MD, PhD, from the Digestive Disease Center and Research Institute, Department of Internal Medicine, SoonChunHyang University School of Medicine, Bucheon, Cheonan, and Seoul, Korea. Indirect diagnostic modalities such as CT, magnetic resonance imaging, and ERCP are sometimes unsatisfactory for …
Modified double-layered suturing for a mucosal defect after colorectal endoscopic submucosal dissection (Origami method) (with video)
Post written by Teppei Masunaga, MD, and Motohiko Kato, MD, PhD, from the Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan. Endoscopic defect closure techniques have been applied to reduce the incidence of adverse events after colorectal endoscopic submucosal dissection (ESD). This retrospective observational study aimed …
Comparative diagnostic performance of different techniques for EUS-guided fine-needle biopsy sampling of solid pancreatic masses: a network meta-analysis
Post written by Antonio Facciorusso, MD, PhD, from the Gastroenterology Unit, Department of Surgical and Medical Sciences, University of Foggia, Foggia, Italy. In the last decade, several EUS fine-needle biopsy (FNB) sampling needles have been developed, and newer end-cutting FNB needles, which feature alterations of the cutting tip, have been found to outperform other needles in …
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